UCB presents positive results from GEMZ phase 3 study at AES showing fenfluramine significantly reduced countable motor seizure frequency in CDKL5 deficiency disorder
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❓ Why did the motor trip? Short circuit / Bearing seizure / Phase imbalance / Overload / Mechanical fault #ElectricalEngineering #MotorProtection #ElectricalFault | Er Muhammad Miyaji
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Sandifer syndrome is often misunderstood and missed. It’s a condition seen in some infants where reflux causes abnormal movements or posturing, like arching, stiffening, or turning the head to one side. It can look scary, but it’s the body’s response to discomfort, not a seizure disorder. Because reflux, feeding difficulty, and discomfort are closely connected, babies with Sandifer syndrome often benefit from a full feeding and oral function evaluation, not just symptom management. When feeding
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ว่าด้วยเร่อง Motor seizure ชักจริง หรือ ชักปลอม (True seizure vs Pseudoseizure) ต้องรู้พฤติการณ์ของชักจริงก่อนถึงจะแยกชักปลอมได้ - Epileptic seizure หมายถึง อาการชักที่เกิดจากการทำงานมากผิดปกติของเซลล์ผิวสมอง (Cortical neuron) ทำให้ปล่อยกระแสประสาทไฟฟ้า (ictal epileptiform discharge) ออกมามากผิดปกติ จากบริเวณเริ่มชัก (ictal onset zone) และอาจจะกระจายไปกระตุ้นสมองส่วนต่างๆ และเกิดอาการแสดงขึ้นตามหน้าที่ของสมองส่วนนั้นๆ เรียกว่า Seizure semiology โดยการชักแต่ล่ะครั้งอาจจะประกอบด้วยอาการชักมากกว่า
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