DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes. Among them, DNA–histone cross-links (DHCs) occur frequently within ...

Chromatin remodelers are ATP-dependent motor proteins that dynamically reorganize chromatin architecture, playing essential roles in gene expression, development, and immune function. Dysregulation of ...

Individual cells divide through a process called mitosis, during which the cell's copied DNA is separated between two resulting daughter cells. Despite recent advances in cell biology, the mechanism ...

Chromatin remodeling plays a vital role in gene regulation, affecting how DNA is accessed. Disruptions in this process can also lead to cancer and other diseases. To better understand how chromatin ...

In the early 1980s, David Gilmour, now an emeritus biochemistry and molecular biology professor at Pennsylvania State University, joined the laboratory of geneticist and biochemist John Lis as a ...