In the embryonic kidney, three types of precursor cells interact with each other to form a three-dimensional structure. Previous studies successfully induced nephron structures via nephron progenitors ...

The human kidney filters about a cup of blood every minute, removing waste, excess fluid, and toxins from it, while also regulating blood pressure, balancing important electrolytes, activating Vitamin ...

A research project has successfully reproduced the pathogenesis of autosomal dominant polycystic kidney disease (ADPKD) from human iPS cells in vitro. Although cysts derived from renal tubules have ...

Genetic and/or environmental perturbations during kidney development can alter the developmental processes that direct branching and nephron formation and could, hence, underlie congenital and ...