(A) scRNA-seq with ST can reveal spatial zonation profiles of gene expression in the normal liver and a detailed cell landscape of the human liver, showing that 50% of liver genes have partitioning ...

Intestinal-specific Hdac3 deletion increases susceptibility to colitis and small intestinal tumor development in mice fed a high-fat diet.

Chronic liver damage can lead to hepatitis, which causes fibrosis of the liver. This buildup of collagen and other fibrous tissue accelerates when hepatic stellate cells become activated during ...

Liver fibrosis is a progressive and potentially reversible condition that results from chronic liver damage, which can be caused by a variety of factors, including metabolic dysfunction-associated ...

The liver's ability to communicate with other organs is crucial for maintaining homeostasis, particularly through signaling pathways. During liver regeneration, communication with organs such as the ...

Researchers at the University of Barcelona found that combining pemafibrate and telmisartan significantly reduces liver fat and cardiovascular risks in MASLD models. The drug duo works better together ...

The prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD), or nonalcoholic fatty liver disease, has increased steadily over past decades. It now affects 38% of adults ...

Low Testosterone May Worsen Fructose-Related Fatty Liver Risk In A Nutshell A mouse study found that low testosterone and high fructose intake together cause significantly more liver fat buildup than ...

Metabolic dysfunction-associated steatotic liver disease is the most common liver disease in the world, affecting about one-third of the adult population. This disorder is characterized by the ...

A mushroom-based supplement called AHCC may prevent the onset of liver fibrosis by targeting key cells before they trigger scarring and damage. With no current cure for cirrhosis, this discovery could ...

Certain fats used in some infant formulas may strain the developing liver and contribute to early signs of steatotic liver disease, according to a new study led by researchers in Virginia Tech's ...