Although DNA is tightly packed and protected within the cell nucleus, it is constantly threatened by damage from normal ...

DNA, though tightly packed in the nucleus, is constantly threatened by damage from metabolism and external stressors. One particularly severe form of DNA damage is the so-called DNA–protein crosslinks ...

A research group is the first in the world to succeed in constructing artificial cell nuclei by injecting purified DNA solution instead of sperm into living mouse eggs. Their findings are published in ...

Researchers at DZHK found that lamin A/C regulates cysteine metabolism, which in turn controls epigenetic gene switches in ...

Researchers at the Francis Crick Institute have shown that the 'pacemaker' controlling yeast cell division lies inside the nucleus rather than outside it, as previously thought. Having the pacemaker ...

When cancer cells are physically squeezed, they mount an instant, high-energy defense by rushing mitochondria to the cell nucleus, unleashing a surge of ATP that fuels DNA repair and survival. This ...

Cancer cells are subjected to high mechanical pressure that leads to a rupture of the nuclear envelope when migrating through narrow tissue structures, as in the case of metastasis. DNA would normally ...

In tissue biopsies, cancer cells are frequently observed to have nuclei (the cell's genetic information storage) that are larger than normal. Until now, this was considered a sign that the cancer was ...

(Nanowerk News) Imagine trying to poke a hole in the yolk of a raw egg without breaking the egg white. It sounds impossible, but researchers at the University of California San Diego have developed a ...

Eukaryotic cells -- i.e. cells with a nucleus -- contain a large number of functional sub-units, so-called organelles. They perform important functions within the cell. Some organelles were ...